About

Codified Genomics was founded in 2013 in Houston, TX, primarily to serve genomic variant interpretation for researchers in the Texas Medical Center. Since then Codified has developed tools to serve clinical genomic interpretation around the country.

Matthew Bainbridge, Ph.D. CEO

Matthew has worked with high-throughput sequencing since its inception. At Canada's Michael Smith Genome Sciences Centre (BCGSC), he constructed the first algorithms for RNA seq, chip-seq, and structural rearrangement discovery for the 454 and Solexa sequencing platforms. He later received his PhD in structural and computational biology and molecular biophysics from his work at the Baylor College of Medicine Human Genome Sequencing Center (BCM-HGSC). There he helped develop the BCM-HGSC’s illumina analysis pipeline, capture-resequencing analytics and co-developed capture reagents, both regional and whole exome including some of the largest capture targets ever sequenced.

His analytic tools were central to the analysis of one the first personal genomes used for medical diagnostics[Lupski]. Later, he led the team that discovered the molecular cause of DRD in siblings. This information was used, for the first time, to alter the management and medications the children received. Later, he used WES to find a novel gene for  a previously undescribed disease, marking one of the first times WES was used to molecularly describe a disease prior to its clinical description. 

Eric Venner, Ph.D. CTO

Eric has a decade of experience using state-of-the-art computing technologies to address scientific problems in computational biology spanning genomic variant analysis, clinical reporting and protein function prediction. He brings extensive experience leading computational analysis teams for large genomics projects. He currently participates in working groups for a large number of NIH-funded sequencing initiatives including All of Us (member of the Technical Operations and Reporting and Clinical Interpretation working groups), eMERGE, CSER (member of the Sequence Analysis and Diagnostic Yield working group) and formerly the UDN (member of the Sequence Analysis working committee). In addition, he is a member of the ClinGen complex disease working group. He has overseen development of a cloud-based data commons backed by AWS and web-portals for the eMERGE project to facilitate collaboration and data exchange. During his PhD and previously in his work as a software engineer he developed high-quality scientific and commercial software tools. At Codified he oversees development and technology decisions.